#efficacy {
  position: relative;
  display: flex;
  flex-direction: column;
}
@media (min-width: 1024px) {
  #efficacy .subheader {
    order: -1;
  }
  #efficacy .subheader .container .wrapper {
    padding-left: 0;
  }
  #efficacy .subheader .container .wrapper .subheader_links {
    justify-content: center;
  }
}
@media (min-width: 1400px) {
  #efficacy .subheader .container .wrapper {
    padding-left: 460px;
  }
  #efficacy .subheader .container .wrapper .subheader_links {
    justify-content: initial;
  }
}
@media (min-width: 1024px) {
  #efficacy .hero {
    margin-top: -1px;
  }
}
#efficacy .container .wrapper {
  padding-left: 120px;
  max-width: 1360px;
  width: 100%;
}
@media (min-width: 1024px) and (max-width: 1600px) {
  #efficacy .container .wrapper {
    padding-left: 70px;
  }
}
#efficacy .pre-accordion {
  margin-bottom: 31px;
}
#efficacy .left-detail {
  position: absolute;
  left: 0;
  width: 15vw;
  bottom: 60px;
}
#efficacy .left-detail img {
  width: 100%;
}
#efficacy .right-detail {
  position: absolute;
  right: 0;
  width: 15vw;
  bottom: -120px;
}
#efficacy .right-detail img {
  width: 100%;
}
#efficacy .first-detail {
  width: 100vw;
  position: absolute;
  left: 0;
}
#efficacy section {
  padding: 0 20px;
  background: url("../../images/clinical-data/clinical-data-bg.webp") no-repeat top;
  background-size: 100% 35%;
  position: relative;
}
#efficacy section .container {
  padding: 47px 0 96px;
  position: relative;
  z-index: 2;
}
#efficacy section .bird {
  position: absolute;
  left: 27px;
  top: 373px;
  z-index: 2;
  width: 300px;
}
#efficacy section .clinical-data__title {
  margin-bottom: 11px;
}
#efficacy section .clinical-data__title h2 {
  margin: 0;
  font-size: 32px;
  line-height: 44px;
  color: #083887;
  margin-bottom: 15px;
  max-width: 1146px;
}
@media (min-width: 1024px) {
  #efficacy section .clinical-data__title h2 {
    font-size: 36px;
    line-height: 40px;
  }
}
#efficacy section .clinical-data__title ul li {
  margin-bottom: 5px;
}
#efficacy section .clinical-data__subtitle {
  font-size: 14px;
  line-height: 22px;
}
#efficacy section .clinical-data__subtitle strong {
  font-size: 17px;
  line-height: 22px;
}
#efficacy section .gradient__container {
  background: linear-gradient(90deg, #ef9600, #2e75d3 50%, #083887);
  border-radius: 14px;
  max-width: 1174px;
  padding: 11px 57px 15px 13.5px;
  margin-bottom: 31px;
}
@media (min-width: 1024px) {
  #efficacy section .gradient__container {
    padding: 11px 26px 11px 27px;
    margin-bottom: 53px;
  }
}
#efficacy section .clinical-data__primary-endpoint,
#efficacy section .clinical-data__secondary-endpoint,
#efficacy section .clinical-data__second_secondary {
  font-size: 23px;
  line-height: 26px;
  color: white;
}
#efficacy section .clinical-data__primary-endpoint strong,
#efficacy section .clinical-data__secondary-endpoint strong,
#efficacy section .clinical-data__second_secondary strong {
  color: white;
}
#efficacy section .clinical-data__primary-endpoint strong:first-child,
#efficacy section .clinical-data__secondary-endpoint strong:first-child,
#efficacy section .clinical-data__second_secondary strong:first-child {
  color: white;
  font-weight: bolder;
  text-transform: uppercase;
}
#efficacy section .clinical-data__primary-endpoint sup,
#efficacy section .clinical-data__secondary-endpoint sup,
#efficacy section .clinical-data__second_secondary sup {
  font-weight: normal;
  color: white;
}
#efficacy section .clinical-data__secondary-endpoint {
  margin-bottom: 0;
  max-width: 1025px;
}
#efficacy section .clinical-data__primary-endpoint {
  font-size: 20px;
  line-height: 22px;
  margin-bottom: 0;
}
@media (min-width: 1024px) {
  #efficacy section .clinical-data__primary-endpoint {
    font-size: 26px;
    line-height: 26px;
  }
}
#efficacy section .clinical-data__primary-endpoint sup {
  font-weight: normal;
  color: white;
}
#efficacy section .clinical-data__second_secondary {
  margin-bottom: 28px;
  margin-top: 46px;
  max-width: 1198px;
}
#efficacy section .clinical-data__second_secondary strong {
  color: #505154;
}
#efficacy section .clinical-data__second_secondary strong:first-child {
  color: #083887;
}
#efficacy section .clinical-data__second_secondary sup {
  color: inherit;
  font-weight: bold;
}
#efficacy .clinical-data-image__wrapper {
  position: relative;
  width: 100%;
  max-width: 1174px;
  margin-bottom: 0;
}
#efficacy .clinical-data-image__wrapper img {
  width: 100%;
}
#efficacy .clinical-data__image-reference {
  font-size: 14px;
  line-height: 20px;
  margin-bottom: 29px;
  padding-left: 10px;
  margin-top: 10px;
}
#efficacy .clinical-data__image-reference p {
  margin: 0;
  margin-bottom: 12px;
  font-size: inherit;
  line-height: inherit;
}
@media (min-width: 1024px) {
  #efficacy .clinical-data__image-reference p {
    margin-bottom: 2.5px;
  }
}
#efficacy .clinical-data__middle-content .midle-copy__content {
  display: flex;
  margin-bottom: 25px;
}
#efficacy .clinical-data__middle-content .midle-copy__content div h3 {
  font-size: 24px;
  line-height: 26px;
  font-weight: bold;
  color: #2e75d3;
  margin-bottom: 5px;
}
#efficacy .clinical-data__middle-content .midle-copy__content div ul li {
  font-size: 17px;
  line-height: 22px;
  margin-bottom: 5px;
}
#efficacy .clinical-data__middle-content .midle-copy__content div:first-child {
  margin-right: 53px;
}
#efficacy .clinical-data__middle-content .midle-copy__content div:last-child {
  max-width: 550px;
}
#efficacy .clinical-data__middle-content .midle-copy__reference {
  font-size: 14px;
  line-height: 18px;
  margin-bottom: 60px;
}
#efficacy .clinical-data__middle-content .midle-copy__wrapper {
  margin-bottom: 25px;
}
#efficacy .clinical-data__middle-content .midle-copy__wrapper .clinical-data__title {
  margin-bottom: 2px;
}
#efficacy .clinical-data__middle-content .midle-copy__wrapper .clinical-data__title h2 {
  margin-bottom: 0;
}
#efficacy .clinical-data__middle-content .midle-copy__wrapper p {
  margin: 0;
}
#efficacy .second-image__reference {
  font-size: 14px;
  line-height: 20px;
  margin-bottom: 29px;
}
#efficacy .clinical-data__button {
  display: flex;
  align-items: center;
  justify-content: center;
  width: 100%;
}
#efficacy .clinical-data__button a {
  max-width: 550px;
  height: 58px;
}
#efficacy .clinical-data__references {
  font-size: 14px;
  line-height: 17px;
  max-width: 1276px;
}
#efficacy .clinical-data__references p:first-child {
  margin-bottom: 28px;
}
#efficacy #rbc-ti-data {
  background: white;
  position: relative;
}
@media (max-width: 1024px) {
  #efficacy #rbc-ti-data {
    padding-top: 50px;
    margin-top: -50px;
  }
}
@media (min-width: 1024px) {
  #efficacy #rbc-ti-data {
    background: #f0f6fd;
  }
}
#efficacy #rbc-ti-data::after {
  content: none;
}
#efficacy #rbc-ti-data .container {
  padding-bottom: 0;
  padding-top: 0;
}
@media (min-width: 1025px) {
  #efficacy #rbc-ti-data .container {
    padding-top: 33px;
    padding-bottom: 58px;
  }
}
#efficacy #rbc-ti-data .clinical-data__image-reference {
  max-width: 1180px;
  margin-bottom: 0;
}
@media (min-width: 1025px) {
  #efficacy #rbc-ti-data .clinical-data__image-reference {
    margin-bottom: 29px;
  }
}
#efficacy #exploratory-data {
  background: #fff;
  overflow: visible;
}
#efficacy #exploratory-data .left-detail {
  top: -270px;
}
@media (max-width: 1500px) {
  #efficacy #exploratory-data .left-detail {
    left: -15vw;
  }
}
#efficacy #exploratory-data .right-detail {
  bottom: 280px;
}
#efficacy #exploratory-data .container {
  padding-top: 20px;
  padding-bottom: 0;
}
@media (min-width: 1025px) {
  #efficacy #exploratory-data .container {
    padding-top: 25px;
    padding-bottom: 32px;
  }
}
#efficacy #exploratory-data .container .clinical-data__banner {
  max-width: 758px;
  margin: 0 auto 14px;
  padding: 16px 30px 16px 43px;
  font-weight: 600;
  background: #083887;
  border-radius: 20px;
  color: white;
  position: relative;
  display: flex;
  align-items: center;
}
@media (min-width: 1024px) {
  #efficacy #exploratory-data .container .clinical-data__banner {
    padding: 18px 32px 17px 42px;
    margin-bottom: 60px;
  }
}
#efficacy #exploratory-data .container .clinical-data__banner .gold {
  color: #ef9600;
}
#efficacy #exploratory-data .container .clinical-data__banner:before {
  content: "";
  position: absolute;
  width: 4px;
  height: calc(100% - 46px);
  background: #ef9600;
  left: 27px;
}
#efficacy #exploratory-data .container .clinical-data__banner p {
  font-size: 22px;
  line-height: 25px;
  text-align: left;
  font-weight: bold;
}
@media (min-width: 768px) {
  #efficacy #exploratory-data .container .clinical-data__banner p {
    font-size: 22px;
    line-height: 28px;
  }
}
#efficacy #exploratory-data .container .clinical-data__banner a {
  text-decoration: underline;
}
#efficacy #exploratory-data .container .image__wrapper {
  max-width: 1200px;
}
@media (min-width: 1024px) {
  #efficacy #exploratory-data .container .image__wrapper {
    margin-bottom: 58px;
  }
}
#efficacy #exploratory-data .container .image__wrapper.mobile img:first-child {
  display: block;
  margin-bottom: 28px;
}
#efficacy #exploratory-data .container .image__wrapper.mobile img:last-child {
  margin: 0 auto;
  display: block;
}
@media (min-width: 600px) {
  #efficacy #exploratory-data .container .image__wrapper.mobile img:last-child {
    max-width: 400px;
  }
}
#efficacy #exploratory-data .container .median-duration__image-reference p {
  margin-bottom: 6px;
}
@media (min-width: 1024px) {
  #efficacy #exploratory-data .container .median-duration__image-reference p {
    margin-bottom: 2px;
  }
}
#efficacy #exploratory-data .container .median-duration__image-reference .hang-item:nth-of-type(2) {
  margin-bottom: 6px;
}
@media (min-width: 1024px) {
  #efficacy #exploratory-data .container .median-duration__image-reference .hang-item:nth-of-type(2) {
    margin-bottom: 0;
  }
}
#efficacy #exploratory-data .median-duration__wrapper > .hang-item {
  margin-bottom: 10px;
}
#efficacy #exploratory-data .median-duration__wrapper > .hang-item:last-of-type {
  margin-bottom: 16px;
}
#efficacy section#hemoglobin-data {
  background: none;
  background-color: #f0f6fd;
}
#efficacy section#hemoglobin-data .container {
  padding-bottom: 20px;
}
#efficacy section#hemoglobin-data .container .hang-item.spaced {
  margin: 4px 0;
}
#efficacy section#hemoglobin-data .container .clinical-data-image__wrapper.mobile {
  width: calc(100% + 30px);
  margin-left: -15px;
}
#efficacy section#hemoglobin-data .container .clinical-data-image__wrapper.mobile .hang-item {
  font-size: 14px;
  line-height: 20px;
  margin-bottom: 32px;
  width: calc(100% - 30px);
  margin-left: 15px;
}
#efficacy section#subgroup-analyses {
  background: none;
  background-color: #fff;
}
#efficacy section#subgroup-analyses .container {
  padding-bottom: 0;
  padding-top: 15px;
  margin-top: 25px;
  border-top: 2px solid #ff6721;
}
@media (min-width: 1024px) {
  #efficacy section#subgroup-analyses .container {
    border-top: none;
    padding-top: 29px;
    margin-top: 29px;
  }
  #efficacy section#subgroup-analyses .container:before {
    content: "";
    position: absolute;
    top: 0;
    left: 50%;
    transform: translateX(-50%);
    width: 100%;
    max-width: 817px;
    height: 2px;
    background: #ff6721;
  }
}
#efficacy section#subgroup-analyses .container .hang-item.spaced {
  margin: 4px 0;
}
#efficacy section#subgroup-analyses .container .clinical-data-image__wrapper.mobile {
  width: calc(100% + 25px);
  margin-left: -13px;
}
#efficacy section#subgroup-analyses .container h4 {
  font-size: 20px;
  line-height: 23px;
  font-weight: bold;
  margin-bottom: 10px;
  color: #0637eb;
}
@media (min-width: 1024px) {
  #efficacy section#subgroup-analyses .container h4 {
    font-size: 32px;
    line-height: 40px;
    max-width: 1000px;
    margin-bottom: 26px;
  }
}
#efficacy section#subgroup-analyses .container .clinical-data__image-reference {
  font-size: 14px;
  line-height: 20px;
  margin-bottom: 25px;
  padding-left: 10px;
  margin-top: 10px;
}
#efficacy section#subgroup-analyses .container .clinical-data__image-reference p {
  margin: 0;
  margin-bottom: 2px;
  font-size: inherit;
  line-height: inherit;
}
#efficacy section#subgroup-analyses .container .clinical-data__image-reference p:first-child {
  font-size: 17px;
  line-height: 20px;
  letter-spacing: -0.1px;
}
#efficacy section#subgroup-analyses .clinical-data-banner__wrapper {
  width: 100%;
  max-width: 740px;
  margin: 0 auto;
}
#efficacy section#subgroup-analyses .clinical-data-banner__wrapper .clinical-data__banner {
  background: linear-gradient(90deg, #ef9600 0%, #2e75d3 40%, #083887 140%);
  padding: 3px;
  border-radius: 16px;
  position: relative;
  max-width: 100%;
  margin: 0 auto 40px;
  position: relative;
  display: flex;
  flex-direction: column;
  max-width: 1175px;
}
@media (min-width: 1024px) {
  #efficacy section#subgroup-analyses .clinical-data-banner__wrapper .clinical-data__banner {
    margin-bottom: 60px;
  }
}
#efficacy section#subgroup-analyses .clinical-data-banner__wrapper .clinical-data__banner:after {
  content: "";
  width: 100%;
  height: 100%;
  background: linear-gradient(90deg, #ef9600 0%, #2e75d3 40%, #083887 140%);
  border-radius: 16px;
  position: absolute;
  top: 8px;
  left: 8px;
}
@media (min-width: 1024px) {
  #efficacy section#subgroup-analyses .clinical-data-banner__wrapper .clinical-data__banner:after {
    top: 15px;
    left: 15px;
  }
}
#efficacy section#subgroup-analyses .clinical-data-banner__wrapper .clinical-data__banner .clinical-data-wrapper {
  display: flex;
  align-items: center;
  justify-content: center;
  position: relative;
  text-align: center;
  z-index: 1;
  background: white;
  border-radius: 14px;
  padding: 12px 11px 12.5px;
}
@media (min-width: 1024px) {
  #efficacy section#subgroup-analyses .clinical-data-banner__wrapper .clinical-data__banner .clinical-data-wrapper {
    padding: 33px 30px 27px 30px;
  }
}
#efficacy section#subgroup-analyses .clinical-data-banner__wrapper .clinical-data__banner .clinical-data-wrapper p {
  font-size: 20px;
  line-height: 26px;
  margin: 0;
  font-weight: bold;
  color: #083887;
  max-width: 95%;
}
@media (min-width: 1024px) {
  #efficacy section#subgroup-analyses .clinical-data-banner__wrapper .clinical-data__banner .clinical-data-wrapper p {
    font-size: 24px;
    line-height: 28px;
  }
}
#efficacy section#subgroup-analyses .clinical-data-banner__wrapper .clinical-data__button a {
  padding: 14px 40px;
}
#efficacy section#next-button {
  background: none;
  background-color: #fff;
}
#efficacy section#next-button .container {
  padding: 0;
}
@media (max-width: 1023px) {
  #efficacy section#next-button .container .__button a {
    padding-left: 90px;
    padding-right: 90px;
  }
}
#efficacy section#references {
  background: none;
  background-color: #fff;
}
#efficacy section#references .container {
  padding: 40px 0 30px;
}

@media (max-width: 1870px) {
  #efficacy section .bird {
    display: none;
  }
}
@media (min-width: 1440px) and (max-width: 1919px) {
  #efficacy .left-detail {
    left: -13vw;
    width: auto;
  }
  #efficacy .right-detail {
    right: -5vw;
    width: auto;
  }
}
@media (max-width: 1439px) {
  #efficacy section .bird {
    display: none;
  }
  #efficacy .clinical-data-image__wrapper {
    margin-left: 0;
  }
  #efficacy #hemoglobin-data .container {
    padding-bottom: 40px;
  }
  #efficacy .left-detail {
    display: none;
  }
  #efficacy .right-detail {
    display: none;
  }
}
@media (min-width: 1024px) and (max-width: 1279px) {
  .hero {
    padding: 30px 20px 19px;
  }
  #efficacy section {
    padding: 0 40px;
  }
}
@media (min-width: 768px) and (max-width: 1024px) {
  .hero {
    padding: 30px 20px 19px;
  }
  #efficacy section {
    padding: 0 20px;
  }
  #efficacy .container .wrapper {
    padding-left: 20px;
  }
  .clinical-data-image__wrapper.mobile {
    display: none;
    text-align: center;
  }
  .clinical-data-image__wrapper.desktop {
    display: block;
  }
}
@media (max-width: 768px) {
  .hero {
    padding: 30px 15px 19px;
  }
  #efficacy section {
    padding-left: 15px;
    padding-right: 15px;
    background-size: 100% 15% !important;
  }
  #efficacy .container .wrapper {
    padding-left: 0px;
  }
  #efficacy .bird {
    display: none;
  }
}
@media (max-width: 1023px) {
  .hero .hero__title h1 {
    font-size: 28px;
    line-height: 30px;
  }
  #efficacy section .clinical-data__title h2 {
    font-size: 22px;
    line-height: 26px;
    font-weight: 600;
  }
}
@media (max-width: 768px) {
  #efficacy .clinical-data__middle-content .midle-copy__content {
    flex-direction: column;
  }
}
@media (min-width: 768px) {
  #efficacy .clinical-data__button a {
    margin-bottom: 32px;
  }
}
/*# sourceMappingURL=clinical-data-efficacy.css.map */